Portal:Spaceflight/On This Day/22 October
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- 1966 - A Molniya-M launches the Luna 12 probe.
- 1967 - A Molniya-M launches a Molniya-1 satellite.
- 1969 - A Proton-K fails to launch the Kosmos 305 probe.
- 1974 - A Soyuz-U launches the Kosmos 690 satellite.
- 1976 - A Molniya-M launches the Kosmos 862 satellite.
- 1977 - A Delta 2914 launches the ISEE 1 and 2 satellites.
- 1979 - A Soyuz-U launches the Kosmos 1142 satellite.
- 1985 - A Zenit-2 launches the Kosmos 1697 satellite.
- 1985 - A Molniya-M launches the Kosmos 1698 satellite.
- 1986 - A Zenit-2 launches the Kosmos 1786 satellite.
- 1986 - A Soyuz-U launches the Kosmos 1787 satellite.
- 1987 - A Soyuz-U launches the Kosmos 1893 satellite.
- 1992 - Space Shuttle Columbia launches on mission STS-52 to conduct microgravity research and deploy the LAGEOS-2 and IRIS satellites.
- 1993 - An Ariane 4 launches the Intelsat 701 satellite.
- 1995 - An Atlas II launches the USA-114 satellite.
- 1997 - A Pegasus-XL launches the STEP-4 satellite.
- 2001 - A PSLV launches the TES satellite.
- 2008 - A PSLV-XL launches Chandrayaan-1, India's first lunar orbiter.